Spiral dynamics in a cardiac electromechanical model with a local electrical inhomogeneity
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[Article] Dynamics of spiral waves in a cardiac electromechanical model with a local electrical inhomogeneity Original Citation: Mesin L. (2012). Dynamics of spiral waves in a cardiac electromechanical model with a local electrical inhomogeneity. Porto, the institutional repository of the Politecnico di Torino, is provided by the University Library and the IT-Services. The aim is to enable open access to all the world. Please share with us how this access benefits you. Your story matters. Spirals in a model of heterogeneous cardiac tissue Spiral dynamics in a cardiac electromechanical model with a local electrical inhomogeneity Luca Mesin The electro–mechanical coupling in the heart is simulated by a three equation model, describing the electric potential, the recovery variable and the mechanical deformation, under the active strain hypothesis. The tissue is anisotropic and electrically inhomogeneous. The generation and dynamics of a spiral wave of excitation is studied. Joint effect of electrical heterogeneity (e.g. induced by ischemia) and mechanical deformation is investigated for an anisotropic, quasi– incompressible model of cardiac electromechan-ical coupling (EMC) using the active strain approach and periodic boundary conditions. Under a specific stimulation protocol, the heterogeneity is able to induce spirals. The interplay between the dimension of the electrical inhomogeneity, the EMC and the mechano-electrical feedback provided by the stretch activated current determine the dynamics of the spiral wave of excitation.
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